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cialis manufacturerCialis is a very important medication that is prescribed in the treatment for erectile dysfunction and also impotency related issues. It has tadalafil as the active ingredient and is known to work by relaxing the muscles in the blood vessels and increasing the blood flow towards the genitals thereby paving way for a firm erection that can last for quite a long time. Cialis also has the potency to treat benign prostatic hypertrophy, otherwise known as enlarged prostate. Cialis is available in the generic form by the name tadalafil. There are many manufacturers of Cialis in US. In this blog, you can know about the various manufacturers that make Cialis.

History of Cialis

From the time Viagra was approved by the food and drugs administration in the year Mar 1998 for the treatment of erectile dysfunction, Pfizer became the only drug company that enjoyed five years of monopoly of distributing the ED med sildenafil citrate. In just the first year, it sold about one billion of Viagra. Later on, Levitra was approved for the same purpose of treating ED and then came the Cialis which was approved by FDA in the year 2003.

Development of Cialis

The development of Cialis has a very interesting beginning. One drug company called Icos had initiated a study about the pDE5 inhibitor in 1993. All ED meds usually work in this process. Interestingly, in the year 1994, one scientist at Pfizer discovered that Sildenafil Citrate enabled patients with heart ailments to get a better erection when they conducted a clinical study. It was then found that they did not test the med IC351 by Icos for ED as later it was discovered that it had similar effect that of another ED pill Viagra. After a year or so, after enough testing, it was discovered that sildenafil citrate had potential effects of treating impotency or ED.

Patent for Cialis by various manufacturers

A Washington based Drug Company, Bothell, Icos which began its operation in creating the powerful ED med, received its first patent in the year 1994. It is however not certain if the patent was given before or after the discovery by Pfizer. Phase1 testing began and after two years, the testing continued for phase2. During phase 2, the year 1997 became the year when Icos conducted its first study in people who were known to suffer from erectile dysfunction. The phase 2 took another two years for the study which later led to the phase 3.

Later in the year 1998, Icos and Eli Lilly and co commercialized the drug for treating ED. In 2002, Cialis was approved in Europe and the next year Lilly and Icos also got the patent for the drug Cialis and was approved by FDA. 

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