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Product Description

Mestinon is a cholinesterase inhibitor indicated for the treatment of myasthenia gravis, and is generically known as pyridostigmine. It comes in syrup and tablet form. The drug is known by various trade names globally. The syrup formulation of the medicine contains 60 mg of pyridostigmine bromide and the other inactive ingredients are lactic acid, glycerin, sodium benzoate, sucrose, sorbitol, and alcohol. The tablet formulation contains stearic acid, silicon dioxide and lactose.


The foremost use of Mestinon is to treat the weakened muscles as a result of myasthenia gravis medical condition. The secondary medical use of the pill is to treat orthostatic hypertension.

According to medical experts, Mestinon is highly effective in the treatment of chronic axonal polyneuropathy. Its off-label medical use is to treat postural tachycardia syndrome as well as to control the symptoms associated with Ehlers-Danlos Syndrome. It strengthens the weakened muscles to a greater extent as it relatively exhibits a prolonged duration of action.


Mestinon should only be taken with water as a whole single tablet. Taking the pill with milk or food of any kind will definitely upset the stomach. The liquid formulation of the medicine should be properly measured with a dose-measuring spoon.

The onset of positive effects gets triggered in the body only when Mestinon is taken in the right dosage strength and at the right time. Doctor’s instruction should be strictly followed at instances when the dose to be administered is titrated.

Patients who are about to undergo surgery whilst taking Mestinon should inform the doctor in advance, as the medication needs to be discontinued for a short period of time.

Side Effects

The serious side effects of Mestinon are weakness in muscle, poor breathing pattern, Problems in proper vision, pain in stomach, diarrhea, vomiting and nausea. The other commonly reported side effects are twitching, muscle cramps, increased salivation, sweating, rashes in skin and blurred vision. Depending upon the medical condition, the nature of side effects may vary with individuals. Abnormality in side effects should immediately be reported to the doctor.

Drug interactions

The major categories of drugs that interact with Mestinon are vitamins, herbal products, over-the-counter drugs and prescription medicines. It is necessary that every individual disclose to their healthcare provider the type of medication that they currently administer and the proposed duration of the course of therapy. This will indeed enable individuals to find out whether or not to discontinue the other medications in order to overcome drug interaction.