Imuran is a class of immunosuppressant drugs that is typically used after a kidney transplant. It is a prescription medicine which was one of the most widely used immunosuppressants for over 50 years.
The active ingredient in Imuran is azathioprine and it works by minimizing the effect of certain immune system cells in the body.
Imuran is also classified as an antimetabolite which means a substance that combines with the enzymes within the cells to tamper with their normal metabolic process. By doing this the drug will easily be able to control the immune system of the body.
Imuran is used to help make the body accommodate the new kidney and prevent its rejection after an organ transplant. For this purpose it is usually used in conjunction with other therapies that also has immunosuppressant qualities.
Aside from this, Imuran is also prescribed for the treatment of rheumatoid arthritis to reduce its symptoms such as inflammation. Even for this purpose it can be combined and used with other medications. Owing to the function of the pill, any slight misuse of the pill will lead to very serious damage.
Using Imuran for the prevention of organ rejection the minimum required dosage without increasing the toxicity of the patient will vary from person to person. Certain people who are sensitive to the medicine will be suggested as an alternative therapy by the doctor. For the management of rheumatoid arthritis, on the other hand, an initial dose of 50 to 100 mg of Imuran is given.
Normally a single dose of Imuran is given to the patient. At instances where the patient feels that the drug’s effects are too much for them, can split the dose by discussing it with their doctor.
Imuran can be taken orally with or without food. The dose can be increased to a maximum of 250 mg.
Certain common side effects of this immunosuppressant are:
More serious side effects of Imuran are:
Imuran may interact with anticoagulants, aminosalicylates such as mesalazine and alkylating agents such as melphalan. Tell your health care facilitator if you are taking any of these medications and any prescription medications in general.