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viagra for wound healingViagra is a well-known medication to treat erectile dysfunction in a man. But, this is not a blog to analyze about it. Instead we are going to discuss about the test results that have been derived based on the topic whether taking Viagra helps to promote wound healing or not. Wound healing is not a simple factor but involves a very long procedure.

Detailed review about Viagra to be taken for wound healing

We are now going to look about the study made on this topic. During the research 25 Sprague Dawley rats were taken and made sure that they weigh anywhere between 200 to 250 grams. This study happened for a longer period and carefully monitored. Four dorsal defects were formed in the rats. The aim of the study is to analyze how effective it is to take Sildenafil citrate for healing the wound.

In this study, there were 4 solutions. First one contained 1% Sildenafil citrate along with carbopol. Second solution contains 5% active ingredient of Viagra with Carbopol. Third solution involved only carbopol without any sildenafil citrate in it. The last is just a 9% Nacl solution. To tell in detail, it was like a gel more than a solution.

All these were applied to each wound of the same rat. They were sacrificed on different days such as third, fifth, seventh, tenth and fourteenth. The effects of the gels were examined properly based on few factors. They are defect area measurement, checking the tissue hydroxyproline levels and histopathological examination.

What effect had Viagra medication had on the wound?

The study was conducted on different days. Each and every day the result was amazing. When Viagra gel is applied on the rat it is found that those defect areas were decreased in a dose independent way in the third day.

When the Sildenafil citrate gel was applied on the regular basis, on the seventh day it became dose dependent. The vascularity started to increase right from third day. In case of considering the strength of acute inflammation, it was very superior with sildenafil citrate from fifth day.

The strength of chronic inflammation and the amount of granulation in the defect areas were higher in case of Viagra groups from the seventh day.

Conclusion of the result

So when Sildenafil Citrate gel is applied on the defect rats, it did show various improvements. They are granulation tissue formation, vascularity, maturation in dose dependent manner and inflammation. This positive effect on the wound would be caused due to the increase in cGMP levels.

In order to inhibit various side effects as well as to get higher concentration on the defect created on the rat, the gel that contained Sildenafil Citrate were applied on it locally.

Moreover, a deeper study has to be made to understand the working mechanism of the effects that are created when Sildenafil Citrate is applied locally. On the other hand, Carbopol had no effects on the wound of the rats.

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