Data relates that Levitra does have the potency to reduce artificial stiffness in heart patients. Though Levitra is widely prescribed for the treatment of erectile dysfunction, the effect of the med on arterial function is still not defined. Certain predictors of cardio vascular system are aortic stiffness, aortic pressure and wave reflections. One research revealed that Levitra can effectively improve aortic pressures, aortic stiffness and also wave reflections in patients having erectile dysfunction. In this blog, you can know more about Levitra and find if Levitra can reduce arterial stiffness in heart patients.
Research on Levitra
About twelve patients in the age group of 50 to 59 were given Levitra in the dosage strength of 20mg on a randomized, placebo-controlled, double blind hypothesis. These patients were evaluated for aortic stiffness along with carotid-femoral pulse velocity, wave reflections, and also aortic pressures were evaluated along with augmentation index (Aix), systolic, diastolic and pulse pressure of the aortic pressure waveform. After three hours of taking Levitra or placebo, aortic pressure, PWV and also Aix were being measured at the baseline. It was found that the pulse wave velocity was decreased significantly and there was a decrease in aortic stiffness being noted.
Findings of the study
Levitra is a selective inhibitor of phosphodiesterase type 5 inhibitor, shortly known as PDE5. This leads to high levels of cyclic guanosine monophosphate i.e. cGMP in corpora cavernosa. The increase in cGMP results in smooth muscle relaxation by the production of nitric oxide in penile arterial vessels and also in the corpora cavernosa, thus paving way for a better erectile functioning. This indicates that the therapeutic use of Vardenafil, the active ingredient in Levitra is closely linked to NO/cGMP system. Some data indicates that the therapeutic potential might involve the myocardium and the coronary as well as the peripheral arteries. In this regard, the drugs that are prescribed for treating erectile dysfunction have some beneficial effects in cardiovascular conditions which includes congestive heart failure and pulmonary hypertension that are related to improving arterial function.
Patients who have coronary artery disease are known to have erectile dysfunction very often. Also, patients who are reporting to have erectile dysfunction as their initial condition have the increased prevalence of coronary artery disease in a silent form. Recently, there have been recognized certain risks like gathering evidence from various studies helped to identify artificial biomarkers like aortic stiffness, central blood pressures and also wave reflection indices.
It was then demonstrated that daily intake of Levitra helped to improve arterial stiffness and also erectile function measurement in men who were having severe vasculogenic erectile dysfunction. Those patients who have been experiencing certain heart conditions took Levitra and reported significant improvement in arterial stiffness.