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Product Description

Baclofen is an antispastic agent as well as a muscle relaxant. The medication was originally developed for treating epilepsy. The active compound is off white in color and is odorless with crystalline formulation. It is partially soluble in water and methanol, whereas least soluble in chloroform.

The inactive ingredients contained in Baclofen are microcrystalline cellulose, colloidal silicon dioxide, povidone, potato starch and magnesium stearate. Its prime working mechanism is by stimulating the GABA-B receptor.


The principal use of Baclofen is to treat cerebral palsy, multiple sclerosis, spastic movement disorders and spinal cord injury. It exhibits central nervous system depressant as well as skeletal muscle relaxant properties. It is also known to offer comprehensive relief from muscle stiffness.

The off-label use of Baclofen is to treat alcohol withdrawal syndrome, however the efficiency of treating such condition is still under investigation. The drug is immediately absorbed from the body. Since it has a very low half-life ranging between 2 to 4 hours, it should be administered all through the day for optimal results.


The dosage strengths for oral administration of Baclofen are 10mg and 20mg.

Baclofen should be taken in the doctor prescribed dosage strength. Never take the pill in decreased dose than the recommended one.

At any circumstance, stiffness in muscles should improve upon two full weeks of the course of therapy with Baclofen.

In case of any dose titration, one should stick on to the doctor’s recommendation. Never stop taking Baclofen without consulting the doctor.

Abrupt withdrawal of the drug causes symptoms like hallucinations and seizures. The medication should be kept in room temperature.

Side Effects

The most probable serious side effects of Baclofen are improper heartbeat, hallucinations, confusion and seizures. The less adverse effects are headache, weakness, feeling of tiredness, dizziness, drowsiness, constipation, and nausea. Some individuals experience an urge to urinate on a very frequent basis. There might be other side effects too that can get triggered in the body. Hence, reporting any abnormal effect in the body to the concerned healthcare provider becomes extremely critical.

Relative contraindications

Baclofen interacts mainly with sedatives, narcotic pain medicines, muscle relaxers, allergic/cold drugs, and pills for treating anxiety, depression and seizures. Interaction can aggravate the sleeplessness induced by the antispastic agent.

As like other drugs, Baclofen is bound to interact severely with over-the-counter drugs, prescription medicines, herbal products and other vitamin supplements. Medication that causes sleepiness should be avoided to a greater extent.